NEWS ALERT: Chemical in popular sugar substitute is found to cause ‘significant health effects’ in new study

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As the most reliable and balanced news aggregation service on the internet, DML News App offers the following information published by Fox News:

Sucralose, a chemical found in the popular zero-calorie sweetener Splenda, has been shown to cause damage to DNA, raise the risk of cancer and cause leaks in the gut lining, according to a new study from North Carolina State University.

Splenda is used as a sugar substitute in thousands of foods, beverages, desserts and candies. The product contains 1.10% sucralose. It is made by Tate & Lyle in the U.K.

The study, published in the Journal of Toxicology and Environmental Health, found that a metabolite of sucralose, called sucralose-6-acetate, is “genotoxic.”


The study notes that sucralose was granted regulatory approval based on 6 claims regarding its safety.  However, the researchers write, “Many scientific research investigations since regulatory approval, however, do not corroborate any of the 6 early historical claims regarding the biological fate or safety of sucralose.”

The study found that sucralose impacts the intestinal tissue.

WebMD simplified the findings of the study, as follows:

The researchers found that sucralose causes DNA to break apart, putting people at risk for disease. They also linked sucralose to leaky gut syndrome, which means the lining of the intestines are worn down and become permeable. Symptoms are a burning sensation, painful digestion, diarrhea, gas, and bloating.

Susan Schiffman, corresponding author of the study and an adjunct professor in the joint department of biomedical engineering at North Carolina State University and the University of North Carolina at Chapel Hill, is quoted as saying, ““In short, we found that sucralose-6-acetate is genotoxic, and that it effectively broke up DNA in cells that were exposed to the chemical.”

Schiffman added, “When we exposed sucralose and sucralose-6-acetate to gut epithelial tissues – the tissue that lines your gut wall – we found that both chemicals cause ‘leaky gut.’ Basically, they make the wall of the gut more permeable. The chemicals damage the ‘tight junctions,’ or interfaces, where cells in the gut wall connect to each other. A leaky gut is problematic, because it means that things that would normally be flushed out of the body in feces are instead leaking out of the gut and being absorbed into the bloodstream.”

Fox News explained:

The U.S. Food and Drug Administration (FDA) first approved sucralose for use in 1998 in 15 food categories. A year later, the agency approved the chemical as a general-purpose sweetener.

CLICK HERE to read the full study.

To get more information about this article, please visit Fox News.

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